Quick Glance: Common Multiple Sclerosis Symptoms

Multiple sclerosis (MS) can affect different neurological functions, so symptoms vary considerably between individuals.

Common multiple sclerosis symptoms include:

  • Reduced or blurred vision in one eye, sometimes with pain during eye movement

  • Double vision

  • Numbness or tingling in the face, body, arms or legs

  • Weakness affecting an arm or leg

  • Muscle stiffness or spasms

  • Difficulty with balance or walking

  • An electric-shock-like sensation down the back when bending the neck forward (Lhermitte’s sign)

  • Fatigue

  • Problems with concentration, memory or information processing

  • Bladder urgency, frequency or difficulty controlling urination

Multiple Sclerosis Symptoms That Should Not Be Ignored

The table below explains symptoms of multiple sclerosis that should not be ignored:

Symptom or Change What It May Indicate
Reduced vision in one eye with pain during eye movement May occur with optic neuritis and requires neurological assessment
New double vision May occur when nerve pathways controlling eye movement are affected
Persistent weakness in an arm or leg A focal neurological change that requires assessment
Persistent numbness or altered sensation May occur when sensory pathways within the central nervous system are affected
Increasing difficulty walking or maintaining balance May reflect neurological involvement affecting movement or coordination
Electric-shock-like sensation when bending the neck forwards May represent Lhermitte’s sign, which can occur with spinal-cord involvement
New bladder problems with other neurological symptoms May occur when nerve pathways involved in bladder control are affected

These symptoms cannot diagnose MS by themselves. Other neurological conditions can cause similar changes, so persistent or unexplained symptoms require proper assessment.

Why Do Multiple Sclerosis Symptoms Occur?

Multiple sclerosis symptoms occur when the immune system attacks the protective covering around nerve fibres in the central nervous system called myelin. This disrupts the normal transmission of electrical signals through the brain, spinal cord and optic nerves.

The symptoms depend on where this damage occurs. Involvement of the optic nerve can cause blurred or reduced vision and pain with eye movement. Damage to sensory pathways may lead to numbness, tingling or unusual sensations, while motor pathway involvement can cause weakness, stiffness or muscle spasms.

MS can also affect pathways involved in balance, coordination, bladder control and cognitive function. This may lead to unsteady walking, urinary urgency, difficulty concentrating or slower information processing.

Multiple Sclerosis Symptoms That Require Immediate Medical Attention

Symptoms of multiple sclerosis generally progress gradually rather than appearing as a sudden neurological event. Sudden neurological symptoms therefore, require immediate medical assessment, particularly when they involve:

  • Sudden weakness or numbness on one side of the body

  • Sudden loss or marked reduction of vision

  • Sudden difficulty speaking or understanding speech

  • Sudden severe loss of balance or coordination

  • Sudden facial weakness

  • Rapidly developing weakness that makes standing or walking difficult

These symptoms may indicate a stroke or another acute neurological condition and require urgent medical assessment.

Symptoms of Multiple Sclerosis Based on Type

The main types of multiple sclerosis differ primarily in how neurological symptoms develop and change over time.

The table below summarises typical multiple sclerosis symptom patterns based on type:

Type of Multiple Sclerosis Typical Symptom Pattern
Relapsing-remitting MS (RRMS) New or worsening neurological symptoms occur during distinct relapses and then partly or completely improve
Secondary-progressive MS (SPMS) Symptoms and disability gradually become more persistent after an earlier relapsing-remitting course
Primary-progressive MS (PPMS) Neurological symptoms gradually worsen from the beginning, usually without clear relapses and remissions

Symptoms of Multiple Sclerosis-Specific Conditions

Certain recognised neurological manifestations can occur as part of MS and may produce more characteristic symptom patterns.

The table below summarises some important symptoms of multiple sclerosis-associated conditions:

MS-Associated Condition Common Symptoms or Features
Optic neuritis Reduced or blurred vision, usually affecting one eye, often accompanied by pain when moving the eye
Lhermitte’s sign A brief electric-shock-like or altered sensation travelling down the back and sometimes into the limbs when the neck bends forward
Spasticity Muscle stiffness, involuntary spasms, pain and difficulty with movement or mobility

Multiple Sclerosis Symptoms in Children

Multiple sclerosis is uncommon in children, but children and teenagers can develop many of the same neurological symptoms seen in adults. Problems with concentration, coordination or school activities may make the changes more noticeable in everyday life.

Possible multiple sclerosis symptoms that may be observed in children by parents are:

  • Changes in vision

  • Numbness or tingling

  • Muscle weakness

  • Poor balance or coordination

  • Tremor

  • Fatigue that interferes with normal activity

  • Difficulty concentrating or thinking clearly

Nearly all children diagnosed with MS have a relapsing-remitting pattern, with episodes of worsening symptoms followed by periods of recovery.

However, none of these symptoms confirms MS in a child. Other childhood conditions can cause similar symptoms, so unexplained neurological changes should be assessed by a specialist.

Can You Have Multiple Sclerosis Without Symptoms?

A person with multiple sclerosis may have periods when no symptoms are noticeable, particularly between relapses in relapsing-remitting MS. Symptoms can improve substantially or even appear to resolve before another episode occurs.

Sometimes, an MRI may show changes that look like those seen in MS even when a person has no typical symptoms. This is known as radiologically isolated syndrome (RIS). Some people with RIS later develop MS symptoms, while others remain symptom-free.

When Can Multiple Sclerosis Symptoms Become Life-Threatening?

Multiple sclerosis does not usually cause a sudden, life-threatening attack. However, sudden or severe neurological changes in someone with MS may represent serious complications.

The table below highlights symptoms that require emergency assessment:

Symptom Why It Is Serious
Sudden one-sided weakness or numbness May indicate a stroke or another acute neurological problem
Sudden difficulty speaking or understanding speech Can be a warning sign of stroke and requires immediate assessment
Sudden loss or marked reduction of vision May indicate an acute neurological or eye-related emergency
Sudden severe loss of balance or coordination Can occur with stroke or another acute neurological condition
Rapidly worsening weakness with inability to walk Requires urgent assessment rather than being assumed to be an expected MS relapse

How are Multiple Sclerosis Symptoms Diagnosed?

Multiple sclerosis cannot be diagnosed from symptoms alone. A neurologist considers the pattern and timing of neurological symptoms, together with examination findings, MRI, and other investigations, while excluding alternative causes.

The following tests and assessments may be used to diagnose symptoms of multiple sclerosis:

Diagnostic Test or Assessment What It Helps Establish
Medical history and neurological examination Identifies patterns involving vision, strength, sensation, reflexes, movement, balance and coordination
MRI of the brain and spinal cord Detects lesions within areas of the central nervous system typically affected by MS
Lumbar puncture Examines cerebrospinal fluid for findings that may support an MS diagnosis
Visual evoked potentials (VEP) Measures how efficiently signals travel along visual pathways
Optical coherence tomography (OCT) Measures retinal nerve fiber thinning after optic neuritis, supportively detecting subtle optic nerve damage
Blood tests Help exclude other conditions capable of causing similar neurological symptoms

The symptoms and findings can have different causes, so no single symptom, MRI finding or laboratory result can confirm MS. A diagnosis requires consideration of the overall neurological picture and specialist assessment.

Frequently Asked Questions (FAQs)

  • Q1. What can be an early sign of multiple sclerosis?

    Ans. Multiple sclerosis may first cause reduced vision in one eye, double vision, persistent numbness, weakness or new balance problems. The first symptom varies according to the nerve pathway affected.
  • Q2. Can multiple sclerosis begin with an eye problem?

    Ans. Yes. Multiple sclerosis can first present with optic neuritis, causing reduced or blurred vision in one eye and pain when the eye moves.
  • Q3. What can an altered sensation from multiple sclerosis feel like?

    Ans. Multiple sclerosis-related sensory changes may feel like numbness, pins and needles, tingling or other unusual sensations. The location depends on the nerve pathways involved.
  • Q4. What is Lhermitte's sign?

    Ans. Lhermitte's sign is a brief electric-shock-like sensation that travels down the back and sometimes into the limbs when the neck bends forward. It can occur with multiple sclerosis, but it is not specific to the condition.
  • Q5. Can multiple sclerosis symptoms improve and then return?

    Ans. Yes. In relapsing-remitting multiple sclerosis, symptoms can worsen during a relapse and then partly or completely improve before another episode occurs.
  • Q6. Can multiple sclerosis affect memory and concentration?

    Ans. Yes. Multiple sclerosis can affect memory, concentration and information-processing speed when brain networks involved in cognitive function are affected.
  • Q7. Does fatigue by itself mean someone has multiple sclerosis?

    Ans. No. Fatigue alone is not specific to multiple sclerosis and has many other causes. MS becomes more concerning when fatigue occurs alongside focal neurological symptoms such as vision loss, weakness or persistent sensory changes.
  • Q8. Which possible multiple sclerosis symptoms need emergency care?

    Ans. Multiple sclerosis symptoms like sudden one-sided weakness or numbness, sudden vision loss, speech difficulty or severe loss of balance require emergency assessment because they may indicate stroke or another acute neurological condition.
  • References

    • https://my.clevelandclinic.org/health/diseases/17248-multiple-sclerosis

    • https://www.ninds.nih.gov/health-information/disorders/multiple-sclerosis-ms

    • https://www.nationalmssociety.org/understanding-ms/what-is-ms/ms-symptoms/spasticity

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