What is Benign Prostatic Hyperplasia?

Benign prostatic hyperplasia is the enlargement of the prostate that puts pressure on the urethra and makes normal urine flow difficult. The prostate is a small gland, roughly the size of a walnut, located directly below the bladder. It surrounds the urethra, which carries the urine from the bladder. As men get older, it is natural for the prostate to enlarge gradually.

But when it puts pressure on the urethra, it may lead to symptoms such as difficulty starting urination, frequent urination, a weak urine stream, and a feeling that the bladder has not emptied.

Types of Benign Prostatic Hyperplasia

Below are the types of benign prostatic hyperplasia (BPH):

  1. Based on Location of Enlargement (Zonal Types)
    • Transitional Zone BPH: The transitional zone surrounds the urethra and is the most common site of BPH. Enlargement in this area can compress the urethra, leading to urinary symptoms.
    • Median Lobe Enlargement: In some men, the middle portion of the prostate grows upward into the bladder neck, which can significantly obstruct urine flow.
    • Lateral Lobe Enlargement: This occurs when the side lobes of the prostate enlarge and narrow the urethral passage, leading to voiding difficulties.
  2. Based on Tissue Type
    • Stromal BPH: In this type, there is an overgrowth of smooth muscle and connective tissue (the stroma) between the inner zone of the prostate. The urinary obstructive symptoms are more severe, and there is greater urethral compression in stromal BPH.
    • Glandular BPH: This type is associated with the overgrowth of epithelial (glandular) cells and results in an enlarged prostate size. Often found in tissue samples taken during TURP (transurethral resection of the prostate) surgery.
    • Mixed BPH: Prostate enlargement involves both glandular (epithelial) and muscular (stromal) cellular growth in mixed BPH. As a result, the enlarged gland physically blocks the urethra, and tense muscles add resistance to the urinary tract.
  3. Based on Clinical Severity
    • Mild BPH: Symptoms are present but cause minimal disruption to daily life.
    • Moderate BPH: Urinary symptoms become more noticeable and may require medical treatment.
    • Severe BPH: Symptoms significantly affect quality of life and may lead to complications such as urinary retention, recurrent infections, or kidney-related problems.

How Common is Benign Prostatic Hyperplasia in India?

BPH is one of the most common urological conditions in men in India, which is increasing parallelly with the growing elderly population in the country.

According to clinical studies, the total number of BPH cases has increased from around 95.5 lakh in 2000 to nearly 1.82 crore in 2019, an increase of almost 90.9%. This shows BPH is a growing and common health concern among adults. Individuals who have diabetes, heart diseases, or a family history of BPH are susceptible to BPH. Sedentary lifestyle (lack of physical activity) and obesity are other risk factors of BPH.

What are the Symptoms of Benign Prostatic Hyperplasia?

As the prostate enlarges, it increases pressure on the urethra, causing a slow deterioration of urine symptoms. Initial symptoms are mostly associated with urine flow, but if left untreated, the condition can progress to bladder dysfunction, recurrent infections or renal-related problems.

Some of the early and advanced symptoms of benign prostatic hyperplasia are:

Early Symptoms Advanced Symptoms
  • Weak urine stream

  • Difficulty starting urination

  • Straining while urinating

  • Feeling of incomplete bladder emptying

  • Post-void dribbling

  • Increased daytime frequency

  • Nocturia

  • Urinary urgency

  • Acute urinary retention

  • Recurrent urinary tract infections

  • Blood in urine (haematuria)

  • Bladder stones

  • Overflow incontinence

  • Hydronephrosis

  • Chronic kidney damage (rare)

  • Persistent bladder dysfunction

What Causes Benign Prostatic Hyperplasia?

Direct causes and risk factors involved with benign prostatic hyperplasia are:

  1. Causes
    • Hormonal Imbalance: When men get old, their testosterone levels drop, and the proportion of estrogen in the prostate rises. This change is thought to stimulate the growth of prostate cells.
    • Dihydrotestosterone (DHT) Accumulation: Dihydrotestosterone (DHT) is a powerful hormone derived from testosterone. As the level of testosterone decreases, the level of DHT in the prostate also increases and stimulates cell growth.
    • Disturbed Prostate Cell Growth Cycle: As a person gets older, the normal growth cycle of prostate cells is upset, with cells building up over time instead of being replaced as they normally would.
  2. Risk Factors
    • Age: BPH has a very low incidence in people under 40 years of age and rapidly increases after 50 years of age.
    • Obesity: Excessive body fat, particularly in the abdomen, increases the level of oestrogen and creates an imbalance in the body's hormones, particularly with respect to the prostate.
    • Hyperinsulinemia: Over time, elevated insulin levels can lead to overgrowth of prostate cells.
    • Sedentary Lifestyle: Physical inactivity has been associated with an increased risk of BPH, whereas increased physical activity appears to have the opposite effect.
    • Diet High in Red Meat and Saturated Fat: This diet (along with low vegetable intake) has been shown to increase the risk of symptomatic BPH.

What are the Stages of Benign Prostatic Hyperplasia?

BPH does not have measurable stages like cancer. Rather, clinicians identify it based on symptom severity using the IPSS (International Prostate Symptom Score) and the presence of complications. This classification allows doctors to choose the most effective treatment method.

Take a look at this classification of benign prostatic hyperplasia in the table below:

Stage Features
Stage 1: Mild BPH Occasional urinary symptoms with minimal effect on daily activities. Usually managed with observation and lifestyle changes.
Stage 2: Moderate BPH Increased urinary frequency, weak stream, and nocturia affecting quality of life. Medicines are commonly prescribed.
Stage 3: Severe BPH Significant urinary obstruction, incomplete bladder emptying, and persistent symptoms despite medication. Surgical treatment may be considered.
Stage 4: Complicated BPH Development of urinary retention, recurrent infections, bladder stones, or recurrent haematuria due to obstruction.
Stage 5: Advanced BPH with Renal Complications Long-standing obstruction causes hydronephrosis or kidney impairment. Urgent intervention is required to prevent permanent kidney damage.

Disease Similar to Benign Prostatic Hyperplasia

Many prostate problems have similar symptoms affecting urination, so it is important to get the right diagnosis. These illnesses can overlap in their symptoms but are very different in their cause, course and treatment.

Benign Prostatic Hypertension (BPH) vs Prostate Cancer vs Prostatitis

Feature Benign Prostatic Hyperplasia (BPH) Prostate Cancer Prostatitis
How it Happens Non-cancerous enlargement of the prostate blocks urine flow. Cancerous growth develops within the prostate gland. Inflammation of the prostate due to infection or other causes.
Location Transition zone of the prostate around the urethra. Usually begins in the peripheral zone of the prostate. Prostate gland.
Associated Symptoms Weak urine stream, frequent urination, nocturia, urgency, incomplete bladder emptying. Early stages may have no symptoms. Advanced disease may cause urinary problems, blood in urine, or bone pain. Painful urination, pelvic pain, fever, urinary frequency, and urgency.
Severity Usually progresses slowly and is rarely life-threatening. Can become life-threatening if untreated. Varies from mild inflammation to severe infection.
Can It Be Reversed? Symptoms can be controlled with medicines or surgery. Depends on the stage and treatment. Many cases improve with appropriate treatment.

What are the Complications of Benign Prostatic Hyperplasia?

Complications associated with benign prostatic hyperplasia include:

  • Acute Urinary Retention: An abrupt and complete inability to urinate. It is the most critical complication of BPH and should be treated with emergency catheterisation to relieve the pressure.

  • Chronic Urinary Retention: Insidious accumulation of a large volume of urine in the bladder, causing it to become permanently weak through stretching and distention.

  • Bladder Stones: When minerals crystallise in stagnant retained urine, it causes pain, infections, and additional blockage.

  • Recurrent UTIs: If urine does not drain properly, bacteria will grow, and infections may recur frequently.

  • Bladder Diverticula: With prolonged straining, pockets (diverticula) can develop in the bladder wall, trapping urine and putting the bladder at risk for infection.

  • Hydronephrosis: If the blockage is present for a long time, the urine accumulates in the kidneys, causing them to swell. This is known as hydronephrosis.

  • Chronic Kidney Disease: Old back-pressure (backed up urine) can lead to permanent kidney damage and, in cases of extreme back-pressure, kidney failure.

When Should I See a Healthcare Provider?

Contact your healthcare provider when:

  • You are unable to pass urine at all, not even for a short time.

  • You wake up three or more times each night to urinate, interfering with sleep regularly.

  • You see blood in your urine more than once.

  • You feel a burning sensation or pain when urinating, along with your other symptoms of urination.

  • You get 2 or more urinary tract infections in six months.

  • You have a feeling of persistent pressure or discomfort in your lower abdomen or pelvic region.

  • Your urinary symptoms have been getting worse over a number of weeks.

  • You experience fever along with difficulty urinating, which can indicate a serious infection.

How is Benign Prostatic Hyperplasia Diagnosed?

The doctor may conduct the following evaluations, tests, and medical examinations to diagnose BPH:

    1. International Prostate Symptom Score (IPSS) The IPSS is a standardised questionnaire with seven questions about urinary symptoms. The answers will be evaluated out of 5 marks each. The total score ranges from 0-7 (mild symptoms), 8-19 (moderate symptoms) and 20-35 (highly severe symptoms). It is the primary instrument to evaluate BPH symptoms.

    2. Digital Rectal Examination (DRE) A doctor puts a gloved finger into the rectum to physically check the size, shape, and texture of the prostate gland.

    3. Prostate-Specific Antigen (PSA) Blood Test PSA is a protein made by the prostate. The blood test for prostate-specific antigen (PSA) is another test used to help diagnose prostate cancer. A higher PSA level may indicate BPH, prostatitis (inflammation of the prostate), or prostate cancer.

Condition PSA Level (ng/mL)
Normal (men under 60) Below 2.5
Normal (men aged 60 to 70) Below 4.0
Borderline / Warrants investigation 4.0 to 10.0
HS / Needs more assessment Above 10.0

PSA is not used to diagnose BPH or cancer. The results are always considered with other clinical findings in mind.

    1. Uroflowmetry Uroflowmetry helps determine the rate and amount of urine flow, or if there is obstruction, and to what extent the obstruction occurs during urination.

    2. Post-Void Residual (PVR) Ultrasound A transrectal or abdominal ultrasound is used to determine how much urine is left in the bladder after a person urinates. It can also be used to directly measure the size of the prostate.

Diagnostic Overview of BPH

Diagnostic Test Purpose What the Doctor Checks
International Prostate Symptom Score (IPSS) Evaluates symptom severity Urinary symptoms and their impact on quality of life
Digital Rectal Examination (DRE) Assesses the prostate gland Size, shape, texture, and abnormalities
Prostate-Specific Antigen (PSA) Blood Test Assesses prostate health PSA levels that may indicate BPH or other prostate conditions
Uroflowmetry Measures urine flow Flow rate and possible urinary obstruction
Post-Void Residual (PVR) Ultrasound Checks bladder emptying Amount of urine remaining after urination

How is Benign Prostatic Hyperplasia Treated or Managed?

Treatment usually involves lifestyle changes for mild symptoms and surgery for advanced symptoms. These include:

  1. Daily Habits
    • Fluid Management: Fluid intake should be reduced in the evening, and caffeine/alcohol should be avoided to minimise nocturia and urgency.
    • Bladder Training: By going to the toilet at regular times and holding off on going to the toilet as soon as you need to, bladder control can gradually get better.
    • Physical activity: Walking and other exercise can help reduce the severity of BPH symptoms and maintain a healthy weight.
    • Nutrition Change: Eating a diet rich in vegetables, fruits, and whole grains and low in red meat and processed foods can help reduce symptom progression.
  2. Medications
    • Alpha-Blockers: These drugs relax the prostate and the bladder neck, thus allowing urine to flow relatively quickly. They do not affect prostate shrinkage.
    • 5-Alpha-Reductase Inhibitors: These medications prevent the conversion of testosterone to DHT, and over several months, the prostate slowly shrinks in size. They are more effective for larger glands.
    • Combination Therapy: Men with larger prostates and more severe symptoms may be treated with both classes simultaneously.
    • Phosphodiesterase-5 Inhibitors: These are used occasionally when BPH is present alongside erectile dysfunction (ED) to treat both conditions.
  3. Surgery
    • TURP (Transurethral Resection of the Prostate): This is the most common BPH surgery in India. A scope is inserted into the penis to take out the blocking prostate tissue. No external cut will be necessary.
    • Holmium Laser Enucleation of the Prostate (HoLEP): A laser procedure that works well for larger prostates. More sophisticated than TURP, with less hospital stay.
    • UroLift: At some centres, there are options like UroLift, which will help to reposition the prostate lobes, for men who wish to avoid compromising their sexual function.

Medicines Used to Treat Benign Prostatic Hyperplasia

For most patients with mild to severe symptoms, doctors advise taking medicines. The medicine prescription depends on the size of the prostate, the intensity of symptoms, age and other connected health issues. Some of the medicines used for treating benign prostatic hyperplasia are:

  • Alpha-blockers (Tamsulosin, Alfuzosin, Silodosin): These medicines allow urine to flow more easily by relaxing the muscles around the prostate and bladder neck.

  • 5-alpha reductase inhibitors (Finasteride, Dutasteride): These medicines gradually shrink the prostate by reducing dihydrotestosterone (DHT) production. They are generally prescribed for men with larger prostate glands and may take several months to achieve maximum benefit.

  • Combination Therapy: Doctors may prescribe an alpha-blocker together with a 5-alpha reductase inhibitor for men with moderate to severe symptoms or significantly enlarged prostates.

  • Phosphodiesterase-5 inhibitors (Tadalafil): Daily low-dose tadalafil may improve urinary symptoms, particularly in men who also have erectile dysfunction.

  • Antimuscarinic Agents (Solifenacin, Tolterodine): These medicines help control urinary urgency and frequency when bladder overactivity accompanies BPH.

  • Beta-3 Adrenergic Agonists (Mirabegron): Mirabegron relaxes the bladder muscle and reduces urgency and frequent urination without significantly affecting urine flow.

Disclaimer: Any medications should be taken only under the direction of a competent healthcare provider. Self-medicating or stopping prescribed medications without medical supervision might worsen symptoms or cause consequences.

Living with Benign Prostatic Hyperplasia in India: Challenges and Medical Care

Here is how living with benign prostatic hyperplasia can affect your daily life:

  1. Managing Daily Activities
    • Planning toilet visits: Frequent urination might interfere with work, travel and social activities. Planning for restroom access can minimise hassle.
    • Limiting evening fluid intake: Reducing fluids a few hours before bedtime may decrease nighttime urination and improve sleep quality.
    • Maintaining regular physical activity: Walking, pelvic floor exercises, and maintaining a healthy weight may help improve urinary symptoms and overall well-being.
  2. Lifestyle Changes and Long-Term Care
    • Following medical treatment consistently: Regular use of recommended medicines and follow-up sessions will help prevent symptom progression and its consequences.
    • Making dietary adjustments: Limiting caffeine, alcohol, and very spicy foods may lessen urine urgency and bladder irritation in some people.
    • Monitoring symptom changes: Tracking of urine flow, frequency, and new symptoms allows early medical attention if the condition deteriorates.
  3. Emotional Wellbeing and Financial Planning
    • Managing sleep disturbances: Frequent night-time urination can interrupt your sleep, leaving you feeling tired and less productive during the day.
    • Addressing emotional concerns: Persistent urinary symptoms may affect confidence and social interactions. Discussing concerns with family members and healthcare providers can provide reassurance.
    • Planning healthcare expenses: Long-term medicines, investigations, and possible surgical treatment can increase healthcare costs. Adequate health insurance may help reduce financial burden.

What is the Prognosis of Prostatic Hyperplasia?

There is no cure for BPH. However, it is extremely manageable with the correct treatment method. Many men can have a good response to both lifestyle changes and medication, which can provide a long period of relief from symptoms and stabilise prostate size. Surgical treatment (TURP) provides long-term relief and is effective in most patients with urinary obstruction.

BPH does not affect life span. However, uncontrolled complications can have an impact on overall health, including kidney damage and recurrent infection. The long-term prognosis is better if treatment is initiated as early as possible.

Benign Prostatic Hyperplasia Treatment Cost in India

The cost of benign prostatic hyperplasia treatment in India varies depending on symptom severity, hospital facilities, city, and the treatment. Many patients can get relief from drugs, but in later stages, they may need a minimally invasive procedure or surgery.

The approximate prices of treatment routinely seen across the Indian hospitals are given in the table below:

Treatment Average Cost Range (₹)
Urologist Consultation ₹800-₹2,000
PSA Blood Test ₹500-₹2,500
Ultrasound with Post-Void Residual ₹1,000-₹2,000
Uroflowmetry ₹600-₹1,400
MRI Prostate (if required) ₹5,000-₹9,000
TURP Surgery ₹70,000-₹6,00,000
HoLEP Surgery ₹1,20,000-₹3,50,000
UroLift Procedure ₹2,00,000-₹4,50,000

Disclaimer: These costs are estimates and may vary depending on the hospital, city, surgeon's expertise, room category, investigations, and individual medical requirements. The final treatment cost should always be confirmed with the treating hospital before planning care.

Does Health Insurance Cover Benign Prostatic Hyperplasia?

Yes. health insurance plans in India usually cover the cost of hospitalisation for BPH. The coverage includes room rent, nursing fees, in-patient diagnostic tests, TURP and HoLEP surgery, and surgeon fees, amongst others. They also pay for pre and post-hospitalisation costs and OPD expenses, depending on the policy terms and conditions.

If BPH is diagnosed before policy purchase, it will be treated as a pre-existing disease (PED). In this case, a maximum waiting period of 36 months will have to be served.

For seniors who have other health issues and are taking care of BPH, critical illness insurance can be a good option in case of a complication such as kidney failure. Such plans provide a lump sum benefit on the diagnosis of the condition and come with a waiting period of up to 90 days.

How Much Health Insurance Coverage is Needed for Benign Prostatic Hyperplasia Treatment?

The cost of benign prostatic hyperplasia treatment in India depends on the severity of the condition and the type of procedure required. The cost of TURP surgery can go up to ₹6 lakh in India. However, the cost of HoLEP surgery is higher, as it is a more advanced procedure.

A medical coverage of at least ₹10 lakh is usually considered adequate for BPH treatment, including hospitalisation costs, surgery expenses, and medications.

FAQs

  • Q1. What is BPH, and is it the same as prostate cancer?

    Ans: No, BPH and prostate cancer are completely different conditions. BPH is an enlarged prostate gland that is not cancerous. However, both conditions can occur simultaneously and share common symptoms.
  • Q2. Does BPH typically start in people when they are in their 50s?

    Ans: BPH rarely occurs before the age of 40. After the age of 50, it becomes more prevalent.
  • Q3. What are the early symptoms of BPH?

    Ans: The initial symptoms of benign prostatic hyperplasia are typically a diminished urine stream, some hesitation before the bladder empties, and a feeling of incomplete bladder emptying. Most of these symptoms are very easy to put down to ageing.
  • Q4. Can BPH be diagnosed from the comfort of your own home?

    Ans: No, there needs to be an evaluation by a medical professional to get a benign prostatic hyperplasia diagnosis confirmed. But you can self-evaluate using the International Prostate Symptom Score questionnaire, available for free online.
  • Q5. What foods should I avoid during benign prostatic hyperplasia?

    Ans: Men with BPH should avoid certain foods that cause inflammation. Alcohol, caffeine, red meat, spicy food, and saturated fats are some examples.
  • Q6. What are your treatment options for BPH apart from surgery?

    Ans: Lots of men can be treated for BPH using medications and lifestyle changes. Patients are often treated with alpha-blockers and 5-alpha-reductase inhibitors to relax the prostate or to shrink its size.
  • Q7. Is BPH seen in men below 50 years of age in India?

    Ans: It depends on the individual risk factors. BPH does not occur before age 40, but it can develop in men in their late 40s, especially if they are overweight, have type 2 diabetes, or have a family history of BPH.
  • Q8. What are the effects of BPH on men's sleep?

    Ans: Nocturia (waking up more than once during the night to urinate) is a common symptom of BPH. Chronic sleep loss may lead to changes in mood, work performance, and cardiovascular function.
  • Q9. Can BPH affect fertility or sexual function?

    Ans: Yes, BPH and its treatment can impact sexual function. Certain medications prescribed for BPH can lead to lower amounts of ejaculation or, occasionally, retrograde ejaculation (semen that backs up into the bladder) occurs.
  • Q10. Is the management of BPH included in health insurance in India?

    Ans: Yes, standard health insurance plans in India cover the cost of treating BPH, including hospitalisation and surgery. If it is a pre-existing condition in older men, a waiting period of up to 3 years may apply, depending on the terms and conditions of your policy.
  • Q11. What are the complications of untreated BPH?

    Ans: Untreated BPH may lead to acute urinary retention (sudden urinary retention), recurrent UTIs, bladder stones, bladder muscle damage, hydronephrosis (swelling of the kidneys), and chronic kidney disease.
  • Q12. How long does recovery take after TURP surgery?

    Ans: In most cases, men will be discharged after TURP within 2–3 days. A catheter remains for 1–3 days after surgery. Complete recovery and return to normal activity typically takes 4–6 weeks after the surgery.
  • Q13. Does BPH come back after surgery?

    Ans: This often depends on the procedure. TURP effectively removes the blocking tissue, and symptoms are normally maintained for several years. However, if the prostate continues to grow, some men might need to have a repeat procedure. HoLEP has a lower recurrence rate than TURP because more tissue is removed.
  • Q14. Are elderly men more likely to develop complications from BPH?

    Ans: Yes, older men have a higher risk of complications caused by BPH or surgery. Co-existing conditions such as hypertension, diabetes, and heart disease may complicate anaesthesia and recovery.
  • Q15. What other related conditions should men with BPH monitor?

    Ans: Men with BPH should also monitor for conditions such as hypertension, type 2 diabetes, metabolic syndrome, obesity, chronic kidney disease, and bladder dysfunction.
  • References

    • https://www.maxhealthcare.in/blogs/psa-test-normal-range

    • https://www.nuhospitals.com/blog/prostate-surgery-cost-2025/

    • https://www.apollohospitals.com/procedures/holmium-laser-enucleation-of-prostate-holep

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